My interest in protein breakdown as a research problem began in l955 at about the time I joined the Biochemistry Department of Yale University. It was known that proteins break down intracellularly in the mature animal. Irwin Rose animalbeginbiochemistry share on social
With the general availability of Windows 8/RT and Surface, I have decided it is time for me to take a step back from my responsibilities at Microsoft. Steven Sinofsky availabilitybackdecide Change image and share on social
I wrote 'The Spy Who Came in from the Cold' at the age of 30 under intense, unshared personal stress and in extreme privacy. As an intelligence officer in the guise of a junior diplomat at the British Embassy in Bonn, I was a secret to my colleagues, and much of the time to myself. John le Carre agebonnbritish share on social
A director in Hollywood in my time couldn't do what he wanted to do. Douglas Sirk directorhollywoodtime Change image and share on social
I know some players like being the centre of attention and I admit that when I first became a player I liked fame, too. But that feeling lasted only for three months. Then I realised what it was really like to be the centre of attention all the time. It isn't all good. Mario Balotelli admitattentioncentre share on social
We are living in the machine age. For the first time in history the comedian has been compelled to supply himself with jokes and comedy material to compete with the machine. Whether he knows it or not, the comedian is on a treadmill to oblivion. Fred Allen agecomediancomedy share on social
Any time you can be with like-minded people, laughing or crying over the same joke or the same scene... For me, it's therapeutic. You just feel a little less alone on the planet. Michael De Luca cryfeeljoke Change image and share on social
I'm a light sleeper. I've never been one of those people who can put their head down and suddenly everything disappears. Nighttime is the time I get most scared, anxious or worried. In those darker moments before waking or sleeping is when I feel most, I don't know, I can turn on myself, and my imagination can take me dark places. Florence Welch anxiousdarkdisappear share on social
The Zombies were really unique - they had elements of jazz and classical music in their songs and songwriting. They had a very, very different sound compared to a lot of their contemporaries at the time. Paul Weller classicalcomparecontemporary share on social
I sing to my wife; it helps me. She was my muse. I've written so many songs about her, to her, with references to her, and still do. She's a big part of my life. We were together for 33 years. It actually does me good - she's with me all that time in that way. Ian McLagan biggoodhave share on social