I had been interested in science from when I was very young, but after a disastrous summer lab experience in which every experiment I tried failed, I decided on graduating from college that I was not cut out to be a scientist. Martin Chalfie collegecutdecide share on social
None of the standard high school science courses made much of an impression on me, but I did enjoy the Advanced Placement Chemistry course I took in my senior year. This course had only eleven students and was taught by a rarity for our school, an exchange teacher from England, Mr. Leslie Sturges. Martin Chalfie advancechemistrycourse share on social
What I am primarily is a neurogeneticist: I use genetics to study problems in neurobiology. The one problem I study primarily... understanding of the sense of touch. Martin Chalfie geneticneurobiologyneurogeneticist Change image and share on social
We know what molecules are needed to sense light - what turns that signal that detects light into an electrical signal. We know how smells are detected. But we have a vast number of senses for which we know what the signal is, but we don't know what the receiver is. Martin Chalfie detectelectricallight share on social
Mainly I study the sense of touch and what the molecules are that transduce touch. And I use mutants in the nematode Caenorhabditis elegans to look at that problem. Martin Chalfie caenorhabditiselegansmolecule Change image and share on social
Scientific inquiry starts with observation. The more one can see, the more one can investigate. Martin Chalfie inquiryinvestigateobservation Change image and share on social
For a decade, I had been studying a transparent worm, the C. elegans. I immediately thought, if you could put the G.F.P. gene into C. elegans, you'd then be able to see biological processes in live animals. Until then, we had to kill them and prepare their tissues chemically to visualize proteins or active genes within cells. Martin Chalfie activeanimalbiological share on social
What I did do a lot as a child was read, and I particularly remember reading all the 'Hardy Boys' books, a set of history books called the 'Landmark Books,' and a series of science books called the 'All About Books.' Martin Chalfie bookboycall share on social
I entered Harvard in 1965 not really knowing what I wanted to do. This confusion seems to have lost me a fellowship. G. D. Searle and Company, the pharmaceutical firm, had their home office in Skokie, and they gave a fellowship each year to a graduate from my high school that was going to major in science in college. Martin Chalfie collegecompanyconfusion share on social
People don't generally listen to scientists much. Martin Chalfie generallylistenpeople Change image and share on social