Mainly I study the sense of touch and what the molecules are that transduce touch. And I use mutants in the nematode Caenorhabditis elegans to look at that problem. Martin Chalfie caenorhabditiselegansmolecule Change image and share on social
People don't generally listen to scientists much. Martin Chalfie generallylistenpeople Change image and share on social
The prize was really for the molecule. In 1962, Osamu Shimomura discovered a protein in a jellyfish that caused it to glow bright green. With colleagues, 30 years later, I was able to insert this G.F.P. gene into bacteria and make them turn green. Martin Chalfie bacteriumbrightcause share on social
None of the standard high school science courses made much of an impression on me, but I did enjoy the Advanced Placement Chemistry course I took in my senior year. This course had only eleven students and was taught by a rarity for our school, an exchange teacher from England, Mr. Leslie Sturges. Martin Chalfie advancechemistrycourse share on social
Trying to understand fundamental processes that take place as organisms develop and how their various cells interact with one another - one can see what happens with those cells by asking questions about the fundamentals of biology. Martin Chalfie biologycelldevelop share on social
I do think of this prize as the GFP prize, and I happen to fortunately be one of the people that goes along for the ride. Martin Chalfie fortunatelygfphappen Change image and share on social
If you do an experiment and it gives you what you did not expect, it is a discovery. Martin Chalfie discoveryexpectexperiment Change image and share on social
For a decade, I had been studying a transparent worm, the C. elegans. I immediately thought, if you could put the G.F.P. gene into C. elegans, you'd then be able to see biological processes in live animals. Until then, we had to kill them and prepare their tissues chemically to visualize proteins or active genes within cells. Martin Chalfie activeanimalbiological share on social