John Gurdon

As a brand new graduate student starting in October 1956, my supervisor Michail Fischberg, a lecturer in the Department of Zoology at Oxford, suggested that I should try to make somatic cell nuclear transplantation work in the South African frog Xenopus laevis.

What do cells do when they see a broken piece of DNA? Cells don't like such breaks. They'll do pretty much anything they can to fix things up. If a chromosome is broken, the cells will repair the break using an intact chromosome.

If you're a filmmaker, and every time you finish a film, you just naturally go, 'Oh, I could have done so much better,' that's not much fun, is it, really? You might as well go pick another profession if that really is how you derive satisfaction from it.