My first attempts to transplant nuclei in Xenopus were completely unsuccessful, because the Xenopus egg, unlike those of other amphibians, is surrounded by an extremely elastic membrane and jelly layer that make penetration by a micropipette impossible. John Gurdon amphibianattemptcompletely share on social
Once the principle is there, that cells have the same genes, my own personal belief is that we will, in the end, understand everything about how cells actually work. John Gurdon beliefcellend Change image and share on social
Shinya Yamanaka's work has involved mice and human cells, and advances the prospect of providing new cells or body parts for patients. John Gurdon advancebodycell Change image and share on social
I get into lab early and leave a bit early, too. So I like to have an hour or two before everybody comes in. John Gurdon biteearlyhour Change image and share on social
The work I was involved in had no obvious therapeutic benefit. It was purely of scientific interest. I hope the country will continue to support basic research even though it may have no obvious practical value. John Gurdon basicbenefitcontinue share on social
If you explain to a patient what can be done and what might be the downsides, let the patient choose; don't have ethicists, priests, or doctors say you may or may not have replacement cells. John Gurdon cellchoosedoctor Change image and share on social
As with most animal eggs, the early events of amphibian development are largely independent of the environment, and the processes leading to cell differentiation must involve a redistribution and interaction of constituents already present in the fertilized egg. John Gurdon amphibiananimalcell share on social
There is no doubt that I was blessed with a considerable amount of luck. John Gurdon amountblessconsiderable Change image and share on social
It is particularly pleasing to see how purely basic research, originally aimed at testing the genetic identity of different cell types in the body, has turned out to have clear human health prospects. John Gurdon aimbasicbody Change image and share on social
The first point to remember is that attempts to clone mice have actually been very unsuccessful for at least a decade. Sheep have been successful. So one asks, 'Where do humans lie?' Most people think they are somewhere between the two, but at least there's a reasonable chance they might be clone-able. John Gurdon askattemptchance share on social