Once the principle is there, that cells have the same genes, my own personal belief is that we will, in the end, understand everything about how cells actually work. John Gurdon beliefcellend Change image and share on social
Within one year of starting work, I had found that the nucleus of an endoderm cell from an advanced tadpole was able to yield some normal development up to the nuclear transplant tadpole stage. John Gurdon advancecelldevelopment Change image and share on social
The importance of the egg's non-nuclear material - the cytoplasm - in early development is apparent in the consistent relation that is seen to exist between certain regions in the cytoplasm of a fertilized egg and certain kinds or directions of cell differentiation. John Gurdon apparentcellconsistent share on social
I get into lab early and leave a bit early, too. So I like to have an hour or two before everybody comes in. John Gurdon biteearlyhour Change image and share on social
If you explain to a patient what can be done and what might be the downsides, let the patient choose; don't have ethicists, priests, or doctors say you may or may not have replacement cells. John Gurdon cellchoosedoctor Change image and share on social
The aim of a nuclear-transplant experiment is to insert the nucleus of a specialized cell into an unfertilized egg whose nucleus has been removed. John Gurdon aimcellegg Change image and share on social
There is no doubt that I was blessed with a considerable amount of luck. John Gurdon amountblessconsiderable Change image and share on social
Shinya Yamanaka's work has involved mice and human cells, and advances the prospect of providing new cells or body parts for patients. John Gurdon advancebodycell Change image and share on social
My first attempts to transplant nuclei in Xenopus were completely unsuccessful, because the Xenopus egg, unlike those of other amphibians, is surrounded by an extremely elastic membrane and jelly layer that make penetration by a micropipette impossible. John Gurdon amphibianattemptcompletely share on social
The first point to remember is that attempts to clone mice have actually been very unsuccessful for at least a decade. Sheep have been successful. So one asks, 'Where do humans lie?' Most people think they are somewhere between the two, but at least there's a reasonable chance they might be clone-able. John Gurdon askattemptchance share on social