James Rothman

One of the major lessons in all of biochemistry, cell biology and molecular medicine is that when proteins operate at the sub cellular level, they behave in a certain way as if they're mechanical machinery.

I became aware of the very complex internal organization in a cell from the basic science classes, and it made me think about how all that could work. It seemed like a great mystery, especially how organelles in the cell can be arranged in three dimensions, and how thousands of proteins could find their way to the right location in the cells.