Garry Shandling

My second or third year in the engineering department, I got very frustrated, and I sat down with myself and had a soul-searching conversation with myself and said, 'What I'd really like to do is see if I can write comedy.' ... I moved to L.A. stone cold. Didn't know anybody; didn't know how to go about it. Really started from scratch.

Here's the thing - I'm single, I haven't been married, I don't have kids yet. If I do have kids I would be interested to see them in my life, so here's a movie for kids and I'm in there and I'm supposed to be kind of funny for kids.

You make your first album, you make some money, and you feel like you still have to show face, like 'I still go to the projects.' I'm like, why? Your job is to inspire people from your neighborhood to get out. You grew up there. What makes you think it's so cool?

In 1967, the world health community launched a global effort to eradicate smallpox. It took a coordinated, worldwide effort, required the commitment of every government, and cost $130 million dollars. By 1977, smallpox had disappeared.