It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code. Francis Crick biochemicalcodedirect Change image and share on social
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid. Francis Crick acidaminocase Change image and share on social
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar. Francis Crick acidaminobalance share on social
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap. Francis Crick basecodonfairly Change image and share on social
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few. Francis Crick baseclassextra Change image and share on social
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material. Francis Crick acidcarrydna Change image and share on social
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid. Francis Crick acidaminocode Change image and share on social
This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map. Francis Crick acidaffectamino Change image and share on social
It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule. Francis Crick acidaminobasis Change image and share on social
