Siri Hustvedt

As one of four daughters, I grew up with an imaginary brother - wondering what it would have been like if one of us had been a boy. There's no question that there was a phantom boy child in my imagination when I was young.

Both depression and anxiety disorders, for example, are repeatedly described in the media as 'chemical imbalances in the brain,' as if spontaneous neural events with no relation to anything outside a person's brain cause depression and anxiety.

The ever quickening advances of science made possible by the success of the Human Genome Project will also soon let us see the essences of mental disease. Only after we understand them at the genetic level can we rationally seek out appropriate therapies for such illnesses as schizophrenia and bipolar disease.