Siddhartha Mukherjee

Why did I write 'The Emperor of All Maladies?' A 56-year-old woman with an abdominal sarcoma, having undergone two remissions and a relapse, asked me to describe what she was battling. By the time I had finished answering her, I realised that I had written 600 pages.

Sidney Farber was a pathologist. He was called a doctor of the dead. He was a pathologist who sort of lived in the basement of the children's hospital in Boston, and he became very interested in childhood leukemia. And Farber began to inject this drug, aminopterin, into young kids, in order to see if he could get a remission.

Every time I see documentaries or infomercials about little kids with cancer, I just freak out. It affects me on the highest emotional level... Anytime I think about it, it makes me sadder than anything I can think of.

Software options proliferate extremely easily - too easily, in fact - because too many options create tools that can't ever be used intuitively. Intuitive actions confine the detail work to a dedicated part of the brain, leaving the rest of one's mind free to respond with attention and sensitivity to the changing texture of the moment.