Rufus Wainwright

I've had my ups and downs, and I definitely have a sense - in America, especially - that once you've made your mark and gotten your Rolling Stone piece and your Grammy nomination, that they're on to the next piece of meat, and they don't necessarily like to follow the twists and turns of an artistic career.

Innate mechanisms endow the visual system with highly specific connections, but visual experience early in life is necessary for their maintenance and full development. Deprivation experiments demonstrate that neural connections can be modulated by environmental influences during a critical period of postnatal development.