Robert Mankoff

The line between humor and bad taste is your audience, in which some people will find everything offensive, and some people will find nothing offensive, but the truth is that most humor originates in what would be called bad taste.

I think funny is just the foundation. I don't really think, to some extent, funny is the absolute most important thing. It should also communicate some idea through the medium of cartooning. Just to be funny is... You know what, the things that you laugh hardest at aren't cartoons.

I was honestly a cartoon kid. I loved cartoons. That was more my dream than anything else. But now, it's the films of people like John Cassavetes and Gena Rowlands. Those are the kinds of characters I want to play, and that's the kind of filmmaking I'm fascinated by.

What do cells do when they see a broken piece of DNA? Cells don't like such breaks. They'll do pretty much anything they can to fix things up. If a chromosome is broken, the cells will repair the break using an intact chromosome.