Randy Schekman

Everything I did in high school was focused on microbiology, looking at things like algae under a microscope for hours on end. When I was 13, I saved up $100 to buy a good used microscope. I was obsessed with microorganisms.

Just as Wall Street needs to break the hold of the bonus culture, which drives risk-taking that is rational for individuals but damaging to the financial system, so science must break the tyranny of the luxury journals. The result will be better research that better serves science and society.

What do cells do when they see a broken piece of DNA? Cells don't like such breaks. They'll do pretty much anything they can to fix things up. If a chromosome is broken, the cells will repair the break using an intact chromosome.