Marcus Brigstocke

I failed to get into drama school, and my best friend told me I should do stand-up instead. I was always doing gags and voices, so he booked a gig for me without telling me. I only had four days to write it. I did a seven-minute set; the first four minutes were terrible, but the last two were amazing.

Innate mechanisms endow the visual system with highly specific connections, but visual experience early in life is necessary for their maintenance and full development. Deprivation experiments demonstrate that neural connections can be modulated by environmental influences during a critical period of postnatal development.