Jane Smiley

Somehow, knowing that Alzheimer's is coming mocks all one's aspirations - to tell stories, to think through certain issues as only a novel can do, to be recognised for one's accomplishments and hard work - in a way that old familiar death does not.

The popular mythology of creative genius depends on beloved stereotypes of the artist in youth and old age: the misunderstood upstart who forces us to see the world afresh; and the revered sage who shows us depths of insight attainable only through a lifetime of hard-won experience.