H. Robert Horvitz

The number of cells in our bodies is defined by an equilibrium of opposing forces: mitosis adds cells, while programmed cell death removes them. Just as too much cell division can lead to a pathological increase in cell number, so can too little cell death.

Time and time again, truly basic studies of simple experimental organisms have proved directly relevant to human biology and human disease. An investment in such basic studies is an effective investment indeed.

My scientific pursuits have led to many opportunities and responsibilities beyond those of simply doing research. For example, as a beginning graduate student, it never occurred to me that the life of a scientist could involve so much travel, something that I have always loved.

What do cells do when they see a broken piece of DNA? Cells don't like such breaks. They'll do pretty much anything they can to fix things up. If a chromosome is broken, the cells will repair the break using an intact chromosome.