Frederick Banting

I very deeply appreciate the honour which you have conferred upon me in awarding the Nobel Prize for 1923 to me and Professor J.J.R. Macleod.

Diabetes mellitus is due to a deficiency of the internal secretion of the pancreas. The main principle of treatment is, therefore, to correct this deficiency.

If a patient became sugar-free and blood sugar normal on a basal requirement diet, the caloric intake was gradually increased until sugar appeared in the urine. The tolerance was thus ascertained.

I have no neighbours other than animals and Joshua Trees.

Twice a week I would receive injections or IV's of Factor VIII which clotted the blood and then broke it down.