Nuclear transplantation is a technique that has enormously facilitated the analysis of these interactions between nucleus and cytoplasm. John Gurdon analysiscytoplasmenormously Change image and share on social
There's a danger of some of the best people saying, 'I don't want a career in science.' John Gurdon careerdangerpeople Change image and share on social
If you explain to a patient what can be done and what might be the downsides, let the patient choose; don't have ethicists, priests, or doctors say you may or may not have replacement cells. John Gurdon cellchoosedoctor Change image and share on social
The work I was involved in had no obvious therapeutic benefit. It was purely of scientific interest. I hope the country will continue to support basic research even though it may have no obvious practical value. John Gurdon basicbenefitcontinue share on social
The first point to remember is that attempts to clone mice have actually been very unsuccessful for at least a decade. Sheep have been successful. So one asks, 'Where do humans lie?' Most people think they are somewhere between the two, but at least there's a reasonable chance they might be clone-able. John Gurdon askattemptchance share on social
For my part, I have worked all my life with eggs and embryos of frogs. Compared to other small animals, these have figured prominently in the world of literature. John Gurdon animalcompareegg Change image and share on social
In principle. what is done is to take the nucleus out of a cell with a very fine micro-pipette or needle and introduce it into an egg. That had been done with amphibians a long time ago, and then there was a long pause of many years before people were clever enough to make that work in the sheep. John Gurdon agoamphibiancell share on social
As a brand new graduate student starting in October 1956, my supervisor Michail Fischberg, a lecturer in the Department of Zoology at Oxford, suggested that I should try to make somatic cell nuclear transplantation work in the South African frog Xenopus laevis. John Gurdon africanbrandcell share on social
Within one year of starting work, I had found that the nucleus of an endoderm cell from an advanced tadpole was able to yield some normal development up to the nuclear transplant tadpole stage. John Gurdon advancecelldevelopment Change image and share on social
It is particularly pleasing to see how purely basic research, originally aimed at testing the genetic identity of different cell types in the body, has turned out to have clear human health prospects. John Gurdon aimbasicbody Change image and share on social