As mechanistic biologists, we are hoping that by understanding how the virus works at the molecular level, we will be able to predict with more accuracy how it will evolve. Jennifer Doudna accuracybiologistevolve Change image and share on social
Understanding how Cas9 is able to locate specific 20-base-pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells. Jennifer Doudna bacteriumbasebillion share on social
The impression sometimes created among the public is that scientists are working away in their labs, and maybe they're not always thinking about the implications of their work. But we are. Jennifer Doudna createimplicationimpression Change image and share on social
There's already a lot of active research going on using the Crispr technology to fix diseases like Duchenne muscular dystrophy or cystic fibrosis or Huntington's disease. They're all diseases that have known genetic causes, and we now have the technology that can repair those mutations to provide, we hope, patients with a normal life. Jennifer Doudna activecrisprcystic share on social
I don't think of myself as a role model, but I can see that I am. Jennifer Doudna modelrole Change image and share on social
We found that CAS9 has the ability to make a double-stranded break in DNA at sites that are programmed by a small RNA molecule. What was so important was that we could really show how the CAS9 protein worked. Jennifer Doudna abilitybreakcas9 share on social